posologyr:posologyr是用于单个剂量优化的R软件包
posologyr
概述
posologyr是用于药物治疗个性化的R软件包，它利用了群体药代动力学（popPK），患者特征以及治疗药物监测的结果。
posologyr提供用于估计药代动力学（PK）参数的函数：
poso_simu_pop()用于通过蒙特卡洛模拟估算popPK参数的先验分布
poso_estim_map()用于根据治疗药物监测的结果计算各个PK参数的最大后验（MAP），也称为经验贝叶斯估计（EBE）
poso_estim_mcmc()用于通过马尔可夫链蒙特卡洛（MCMC）估计各个PK参数的后验分布
剂量优化功能包含在posologyr ：
poso_time_cmin()达到目标谷浓度（Cmin）所需的时间
poso_dose_auc()达到目标AUC的最佳剂量
poso_dose_ctime()在任何给定时间达到目标浓度的最佳剂量
Posologyr要求写在一个
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